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Emamzadah S, Tropia L, Halazonetis TD (2011) Crystal structure of a multidomain humanp53 tetramer bound to the natural CDKN1A (p21) p53-response element. Enoxaparin isdesigned to be administered subcutaneously to ensure adequatevascular absorption and reduce the risk of a local hematoma.Subcutaneous enoxaparin has a moderate onset of action(3–5 hours) with a half-life of 4–7 hours leading to approximately12 hours of therapeutic effect. Tohelp illustrate this point, and to begin to emphasize the factthat the toxicity is a function of dose, the reader is invited totake the following pop quiz.

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